Interstate 10 eastbound was closed at 40th Street due to a serious crash involving three vehicles during rush hour Thursday.
Five people were transported to an area hospital with serious injures. One of them later died.
The Arizona Department of Transportation urged drivers to use Loop 202 as an alternate route. Westbound lanes were not affected.
All of the lanes were back open about 6 p.m. No other information is available on the victims.
Investigators are trying to determine how the crash happened.
Live traffic video: myfoxphoenix.com/live2
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