Scientists Discover Hormone Blocks Pot "High" - Fox 2 News Headlines

Scientists Discover Hormone Blocks Pot "High"

Posted: Updated:
 French researchers have discovered that a naturally occurring hormone acts as a defense in the brain against the psychoactive effects of marijuana consumption.

The hormone, pregnenolone reduces the activity of a brain molecule that acts as a cannabinoid receptor.
 
Researches think the discovery could help people with addictions to marijuana, as well as allowing people to take medical marijuana without the behavioral effects.
 
The study was published in the journal Science.
 
About 147 million people globally – or about 2.5 percent of the population – use cannabis, according to the World Health Organization.

While cannabis products can alleviate symptoms of depression, glaucoma, spasms, and nausea associated with cancer and AIDS, they are also known to impair brain development, memory and lung function, and some say they can lead to addiction.

Researchers discovered the previously unknown role of pregnenolone when they administered high doses of cannabis to lab rats, on the order of three to 10 times more than the typical human marijuana smoker might be exposed to, Piazza told AFP.

The high doses of cannabis raised the brain's level of pregnenolone, which blocked the harmful effects of THC on the brain.

They also did tests in the lab on human cell lines – not human patients – that showed a similar blocking effect.

"We hope to be able to start clinical trials in people in a year to a year and a half," Piazza told AFP.

  • Share ThisMore>>

  • Anaheim's Wonderful WonderCon

    Anaheim's Wonderful WonderCon

    Saturday, April 19 2014 9:01 PM EDT2014-04-20 01:01:06 GMT
    It's Easter weekend and while some may be spending their time at Mass, there is a group of passionate people showing up in mass to celebrate their favorite superheroes at the Anaheim WondeCon.
    It's Easter weekend and while some may be spending their time at Mass, there is a group of passionate people showing up in mass to celebrate their favorite superheroes at the Anaheim WondeCon.
  • Kidnapping "Prank" Goes Bad, Parents Not Amused

    Kidnapping "Prank" Goes Bad, Parents Not Amused

    Friday, April 18 2014 1:58 PM EDT2014-04-18 17:58:38 GMT
    Twins brothers with a YouTube channel filled with their pranks say they weren't trying to make a joke. Serious intentions or not, a park full of parents were not amused by their latest stunt. This video is a must-see!
    Twins brothers with a YouTube channel filled with their pranks say they weren't trying to make a joke. Serious intentions or not, a park full of parents were not amused by their latest stunt. This video is a must-see!
  • Griffith Park Mountain Lion Found Sick, Possibly Poisoned

    Griffith Park Mountain Lion Found Sick, Possibly Poisoned

    Thursday, April 17 2014 3:26 PM EDT2014-04-17 19:26:14 GMT
    Rat poison may be responsible for the sorry condition of a wild mountain lion in LA's Griffith Park. The mountain lion is known to the National Park Service as ‘P-22'.
    Rat poison may be responsible for the sorry condition of a wild mountain lion in LA's Griffith Park. The mountain lion is known to the National Park Service as ‘P-22'.
Powered by WorldNow

WJBK-TV | Fox 2
16550 West Nine Mile Rd.
Southfield, MI 48075

Main Station: (248) 557-2000
Newsroom: (248) 552-5103

Didn't find what you were looking for?
All content © Copyright 2000 - 2014 Fox Television Stations, Inc. and Worldnow. All Rights Reserved.
Privacy Policy | Terms of Service | Ad Choices